Dissolution Test Apparatus

The Dissolution rate of a drug from the solid state is defined as the amount of drug substance that goes into solution per unit time under standardized conditions of liquid / solid interface, temperature, and solvent composition. Dissolution Tests are conducted to determine the drug release patterns, physiological availability and bioavailability of formulated drug products. It is also used as a quality control tool. The Koehler Dissolution Apparatus provides state-of-theart dissolution testing with advanced features, which supports USP 1, 2, 5 & 6. This product is designed on the basis ofspecifications recommended by international regulatory bodies and the future needs of the Pharmaceutical Industry. Advanced, Micro-Controller based User-friendly, complies with current USP, IP & EP specifications Splash waterproof keyboard: Alphanumeric polyester soft keys for keyboard Molded water bath with 6+2 (3+1 & 3+1) vessel configuration enables comparative studies Built-in immersion pump for uniform water circulation with audible, low water level alarm with indication on display for safety Mono shaft design with easy changeover between Apparatus I & II eliminates routine height validation as per USP Tablet dispenser-drops 6 dosage forms at a single instance (Optional) Low Evaporation Lids: The conical shape low evaporation recovery lids reduces media loss during long run Integrated pre-centered lids; no manual removal or positioning of lids. This ensures automatic vessel centering and precise positioning of paddle/basket with shaft without any special tool as per pharmacopeia requirements State-of-the-art design: Easy placement and locking of vessels, the Ease-align system allows the vessels to simply slide into the place (Bionet Locking). Once placed, vessels do not float even when empty Facility to monitor Vessel temp., with an external RTD Temperature Sensor (PT100) The Dissolution Tester meets all requirements relating to validation, qualification and calibration Appropriate qualification documents (I.Q. / O.Q.) can be supplied with the instrument Features of the Automatic and Plus Dissolution Apparatus include: facility to RINSE the entire sampling path in between sampling time point to eliminate contamination & carryover. Specially developed cleaning system to clean the entire sampling path after each run.