Spinsolve 80 MHz

Magritek | The worlds leading high performance 80 MHz Benchtop NMR

France-Belgium-Netherlands-Luxembourg joint Magnetic Resonance Conference,...

Bordeaux Polymer Conference, Bordeaux, FR

Annual Meeting on Reaction Engineering...

Monitoring Chemical Reactions...

Optimized Performance combined with highest Versatility.

Optimum solvent suppression performance for samples in protonated solvents

Structure verification of Brucine

F on all systems + X nuclei for dual channel systems

Sensitivity: 280:1 (Single channel for 1% Ethyl Benzene)

Sensitivity: 200:1 (Dual channel for 1% Ethyl Benzene)

3D PFG gradients optimized for gradient-enhanced methods

Optional PFG gradients for diffusion spectroscopy (>0.5 T/m)

External Hardware Lock with no need for deuterated solvents

Suitable for on-line reaction monitoring

Compatible with automatic sample changer

Dimensions: 58 x 43 x 40 cm (23” x 17” x 16”)

Sensitivity measured in a single scan on a 1% ethylbenzene sample dissolved in deuterated chloroform. The signal used for the calculation is the one of the methylene group and the noise is calculated for a signal free region between the aromatic and the methylene signa

The best performance for online reaction monitoring

Metabolites produced by S. Cereviciae during Glucose Fermentation

processes like fermentations. The high sensitivity of

possible to detect metabolites produced at sub millimolar concentrations in just

minutes. In this particular example, solvent suppression

during the fermentation process. The residual water

possible to detect metabolites very close to the solvent

The Spinsolve 80 ULTRA device was used in combination with our reaction monitoring software package

to follow the course of a reaction on-line and also to determine its stereochemical outcome. As an example, the well-known Horner-Wadsworth-Emmons reaction (HWE reaction) was carried out and the result is

shown in the figure below. The HWE reaction was essentially developed to form the E-diastereoisomer as

the reaction product in favour of the corresponding Z-counterpart.

Spinsolve 80 MHz Spectra examples

Operating frequency: 80 MHz (1H)

Spinsolve 80: <0.35 Hz (50%) / <15 Hz (0.55%) / <30 Hz (0.11%)

Spinsolve 80 Ultra: <0.2 Hz (50 %) / <8 Hz (0.55%) / <16 Hz (0.11%)

(Single channel): >280:1 for 1% Ethyl Benzene

(dual channel): >200:1 for 1% Ethyl Benzene